PRX Derm Perfexion & PRX Plus: Advanced Skin Rejuvenation, No Downtime

By: Dr. Kristen Blume

11/24/2025

If you are looking for a treatment that delivers brighter, firmer, more youthful-looking skin without peeling, needles, or downtime, you’re going to love the newest additions to the Beauty by Blume treatment menu: PRX Derm Perfexion and PRX Plus by WIQO.

These innovative bio-revitalization treatments are designed to stimulate collagen, smooth texture, and improve pigmentation - all while keeping the skin barrier intact. Whether you want a subtle refresh or more targeted correction, PRX offers a powerful, year-round solution for radiant, healthy skin.

What Is PRX Derm Perfexion?

PRX Derm Perfexion is a non-peeling, no-downtime skin rejuvenation treatment that gently stimulates collagen beneath the surface. Its unique formulation uses a blend of hydrogen peroxide, 33% TCA, and kojic acid to brighten, tighten, and refresh the skin without the redness or peeling associated with traditional chemical peels.

It’s perfect for improving:

  • Dull or uneven skin tone
  • Mild laxity and crepey skin
  • Fine lines
  • Enlarged pores
  • Textural irregularities
  • Specifically targets acne scarring, rosacea, and stretch marks

What Is PRX Plus?

PRX Plus is the more intensive sister treatment to Derm Perfexion. While it uses a similar technology, PRX Plus is formulated to reach deeper into the dermis for enhanced lifting, tightening, and collagen stimulation.  The formulation specifically targets excess melanin to visibly reduce hyperpigmentation and dark spots, resulting in a clearer, more even skin tone.

PRX Plus is ideal for:

  • More advanced skin laxity
  • Moderate crepey skin (face, neck, chest, body)
  • Deeper lines
  • Textural concerns
  • Hyperpigmentation or sun spots
  • Those wanting more dramatic rejuvenation without downtime

PRX Plus is a great option for patients wanting both firmness and glow.

How Do the Treatments Work?

Both PRX Derm Perfexion and PRX Plus are applied with a special massage technique that helps the active ingredients penetrate into the dermis. The hydrogen peroxide modulates the TCA, allowing collagen stimulation without surface injury.

There’s no peeling or downtime - just tighter, fresher, more radiant skin.

Most patients complete a series of 4–5 treatments, spaced out every 1-2 weeks.

Who Is PRX Best For?

PRX is an excellent option if you want:

  • Fresher, smoother, brighter skin
  • A non-invasive collagen boost
  • Improvement in lines, texture, or pigmentation
  • A treatment that fits into a busy lifestyle
  • A no-downtime alternative to lasers or peels
  • Safe options for melanin-rich skin

PRX is especially beneficial for patients wanting more pronounced tightening or rejuvenation of the neck, lower face, chest, or body without downtime.

Why I am Excited to Offer PRX

After seeing how many of my patients want glowing, younger-looking skin without downtime, PRX was the perfect addition to my treatment menu. It fills the gap between injectables and more intensive energy-based procedures - giving you meaningful, lasting results with zero interruption to your routine.

These treatments also pair beautifully with many of my most popular services, including: Opus Plasma, Skinvive, Salmon DNA (polynucleotides) Mesoneedling, Botox and filler.

Ready to Experience PRX?

Whether you choose Derm Perfexion for glow and clarity or PRX Plus for deeper tightening and rejuvenation, these treatments offer a powerful, modern approach to collagen stimulation.

Schedule your consultation to see which option is right for you!

* All information subject to change. Images may contain models. Individual results are not guaranteed and may vary.